Preheat oven to 375°F (190°C) and line a baking sheet with parchment paper.
 In a large bowl, combine sausage, softened cream cheese, drained Rotel, shredded cheddar, Bisquick, garlic powder, onion powder, and black pepper.
 Mix thoroughly until everything is well combined.
 Roll the mixture into 1–1½ inch balls and place them on the prepared baking sheet.
 Bake for 18–22 minutes until the sausage balls are golden brown and cooked through.
 Let them cool slightly, then garnish with chopped parsley if desired and serve warm.