Preheat the oven to 375°F and lightly grease a large baking dish.

Cook the pasta until just tender, then drain and set aside.

Heat olive oil in a skillet and brown the ground beef until fully cooked.

Season the beef with garlic powder and Italian seasoning, stirring well.

Add the pizza sauce to the beef and simmer briefly until combined.

In a large bowl, mix the cooked pasta with the meat sauce evenly.

Transfer the pasta mixture into the prepared baking dish.

Sprinkle mozzarella and cheddar cheese generously over the top.

Arrange pepperoni slices evenly across the cheese layer.

Bake uncovered for 25–30 minutes until bubbly and golden.